Endocrine Abstracts

Background: Gestational diabetes mellitus (GDM) is defined as glucose intolerance resulting in hyperglycaemia of variable severity, with onset or first recognition during pregnancy. GDM is a risk factor for dysglycaemia in later life. The objective of the study was to determine the impact of GDM on glucose tolerance in the short term post-delivery in a cohort of women who attended the Lagos University Teaching Hospital (LUTH)Study Design: This was a pros...

Introduction: Insulinomas are rare pancreatic neuroendocrine tumours (PETS), which are usually benign and sporadic. They secrete insulin, and hence present with hypoglycaemia. We report a case of insulinoma presenting as seizures.Case Presentation: The patient, a 16-year-old female, first had an episode of convulsion a year prior to referral to the Endocrine Clinic. She was managed at a private clinic with intravenous fluid (name unknown) and later comme...

Background: Diabetic foot disease is a major cause of morbidity and mortality in people living with diabetes. It is a leading cause of minor or major limb loss with attendant huge economic ruins. Objective: The aim of the study was to determine pattern of presentation of diabetic foot ulcer (DFU), assess co-morbid conditions at admission and determine the overall outcome of patients managed over the 5 year study period. Materials a...

Background and objectives: Hyperglycaemic emergencies (HE) are the most common acute complication of diabetes and are associated with relative or absolute insulin deficiency, volume depletion, impaired mental status and metabolic derangements. Hyperglycaemic emergencies are associated with high morbidity and mortality if not properly managed. We investigated the pattern of hyperglycaemic emergencies at Obafemi Awolowo University Teaching Hospital, Ile-Ife, South-western Nigeri...

Introduction: Klinefelter syndrome is the commonest sex chromosomal disorder in which the normal male karyotype 46XY, has at least one extra X chromosome. The commonest form is the 47XXY aneuploidy. It is characterized by hypergonatrophic hypogonadism, and associated with infertility and cardio-metabolic abnormalities. We report a case of a 36year old man who presented in our Endocrinology clinic in Ngeria.Case Presentation:</str...

Background: T2DM has been described as a complex mix bag of insulin resistance and β-cell defects in varying proportions. Several works have described in quantitative terms insulin resistance among diabetics and its relationship with proteinuria, the relative contribution of β- cell dysfunction have largely been extrapolated. This work is an attempt to provide the missing link in our clime.Objectives: The study aims to describe, in quantitative...